
The spectrofluorometer Fluoromax 4 available at CICS-UBI is equipped with MicroMax 384 (microwell-plate reader able to accept plates with up to 384 wells) and measures fluorescence of liquid samples in high throughput screening, with detection of emission spectra out to 1700 nm and time correlated single photon counting lifetime measurements of 25ps. The sensitivity of this spectrofluorometer is generally reported as a minimum measurable concentration of a fluorophore (commonly Fluorescein), or the signal-to-noise ratio (S/N) of the Raman scattering peak of water. Example of applications are monitoring molecule stability and folding of nucleic acids or proteins to identify targets for structure-based drugs, kinetic studies, measurement of smaller samples to detect smaller changes and absolute quantum yields.